array nature communications Search Results


cv reference nature communications | 2025  (Gamry Instruments)
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Gamry Instruments cv reference nature communications | 2025
Cv Reference Nature Communications | 2025, supplied by Gamry Instruments, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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chip dna clean nature communications  (Zymo Research)
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Zymo Research chip dna clean nature communications
Chip Dna Clean Nature Communications, supplied by Zymo Research, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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genechip mouse gene 2.0 st arrays  (Thermo Fisher)
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Thermo Fisher genechip mouse gene 2.0 st arrays
Genechip Mouse Gene 2.0 St Arrays, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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microarray data  (Agilent technologies)
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Agilent technologies microarray data
PTK7 expression is upregulated in breast cancer. (A) Box plots of PTK7 expression in breast invasive carcinoma (BRCA) using GEPIA: Gene Expression Profiling Interactive Analysis system ( http://gepia.cancer-pku.cn/ ). BRCA tumor (T) and non-tumor (N) TCGA normal and GTEx dataset included 1,085 tumor cases (T) and 291 non-tumor cases (N) was selected to observe the expression of PTK7. (B) IHC staining of PTK7 expression in breast cancer tissue <t>microarray.</t> (C) Representative images from PTK7 IHC staining in Luminal A, Luminal B, HER2(+) and TNBC subtypes of breast cancer tissues. Magnification, ×200; scale bars, 100 μm. (D) Scatter dot plots of PTK7 expression in tumors with different molecular subtypes. Data were analyzed using one-way ANOVA and Tukey’s multiple comparisons test and are shown as mean ± s.d. * P < 0.05, ** P < 0.01, **** P < 0.0001. ns, no significance.
Microarray Data, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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microarray data - by Bioz Stars, 2026-04
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array nature communications  (V&P Scientific)
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V&P Scientific array nature communications
PTK7 expression is upregulated in breast cancer. (A) Box plots of PTK7 expression in breast invasive carcinoma (BRCA) using GEPIA: Gene Expression Profiling Interactive Analysis system ( http://gepia.cancer-pku.cn/ ). BRCA tumor (T) and non-tumor (N) TCGA normal and GTEx dataset included 1,085 tumor cases (T) and 291 non-tumor cases (N) was selected to observe the expression of PTK7. (B) IHC staining of PTK7 expression in breast cancer tissue <t>microarray.</t> (C) Representative images from PTK7 IHC staining in Luminal A, Luminal B, HER2(+) and TNBC subtypes of breast cancer tissues. Magnification, ×200; scale bars, 100 μm. (D) Scatter dot plots of PTK7 expression in tumors with different molecular subtypes. Data were analyzed using one-way ANOVA and Tukey’s multiple comparisons test and are shown as mean ± s.d. * P < 0.05, ** P < 0.01, **** P < 0.0001. ns, no significance.
Array Nature Communications, supplied by V&P Scientific, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bioanalyzer high sensitivity dna chip  (Agilent technologies)
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Agilent technologies bioanalyzer high sensitivity dna chip
PTK7 expression is upregulated in breast cancer. (A) Box plots of PTK7 expression in breast invasive carcinoma (BRCA) using GEPIA: Gene Expression Profiling Interactive Analysis system ( http://gepia.cancer-pku.cn/ ). BRCA tumor (T) and non-tumor (N) TCGA normal and GTEx dataset included 1,085 tumor cases (T) and 291 non-tumor cases (N) was selected to observe the expression of PTK7. (B) IHC staining of PTK7 expression in breast cancer tissue <t>microarray.</t> (C) Representative images from PTK7 IHC staining in Luminal A, Luminal B, HER2(+) and TNBC subtypes of breast cancer tissues. Magnification, ×200; scale bars, 100 μm. (D) Scatter dot plots of PTK7 expression in tumors with different molecular subtypes. Data were analyzed using one-way ANOVA and Tukey’s multiple comparisons test and are shown as mean ± s.d. * P < 0.05, ** P < 0.01, **** P < 0.0001. ns, no significance.
Bioanalyzer High Sensitivity Dna Chip, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human brunello crispr knockout pooled library nature communications  (Addgene inc)
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Addgene inc human brunello crispr knockout pooled library nature communications
PTK7 expression is upregulated in breast cancer. (A) Box plots of PTK7 expression in breast invasive carcinoma (BRCA) using GEPIA: Gene Expression Profiling Interactive Analysis system ( http://gepia.cancer-pku.cn/ ). BRCA tumor (T) and non-tumor (N) TCGA normal and GTEx dataset included 1,085 tumor cases (T) and 291 non-tumor cases (N) was selected to observe the expression of PTK7. (B) IHC staining of PTK7 expression in breast cancer tissue <t>microarray.</t> (C) Representative images from PTK7 IHC staining in Luminal A, Luminal B, HER2(+) and TNBC subtypes of breast cancer tissues. Magnification, ×200; scale bars, 100 μm. (D) Scatter dot plots of PTK7 expression in tumors with different molecular subtypes. Data were analyzed using one-way ANOVA and Tukey’s multiple comparisons test and are shown as mean ± s.d. * P < 0.05, ** P < 0.01, **** P < 0.0001. ns, no significance.
Human Brunello Crispr Knockout Pooled Library Nature Communications, supplied by Addgene inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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proteome profiler mouse chemokine array kit nature communications  (R&D Systems)
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R&D Systems proteome profiler mouse chemokine array kit nature communications
PTK7 expression is upregulated in breast cancer. (A) Box plots of PTK7 expression in breast invasive carcinoma (BRCA) using GEPIA: Gene Expression Profiling Interactive Analysis system ( http://gepia.cancer-pku.cn/ ). BRCA tumor (T) and non-tumor (N) TCGA normal and GTEx dataset included 1,085 tumor cases (T) and 291 non-tumor cases (N) was selected to observe the expression of PTK7. (B) IHC staining of PTK7 expression in breast cancer tissue <t>microarray.</t> (C) Representative images from PTK7 IHC staining in Luminal A, Luminal B, HER2(+) and TNBC subtypes of breast cancer tissues. Magnification, ×200; scale bars, 100 μm. (D) Scatter dot plots of PTK7 expression in tumors with different molecular subtypes. Data were analyzed using one-way ANOVA and Tukey’s multiple comparisons test and are shown as mean ± s.d. * P < 0.05, ** P < 0.01, **** P < 0.0001. ns, no significance.
Proteome Profiler Mouse Chemokine Array Kit Nature Communications, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


PTK7 expression is upregulated in breast cancer. (A) Box plots of PTK7 expression in breast invasive carcinoma (BRCA) using GEPIA: Gene Expression Profiling Interactive Analysis system ( http://gepia.cancer-pku.cn/ ). BRCA tumor (T) and non-tumor (N) TCGA normal and GTEx dataset included 1,085 tumor cases (T) and 291 non-tumor cases (N) was selected to observe the expression of PTK7. (B) IHC staining of PTK7 expression in breast cancer tissue microarray. (C) Representative images from PTK7 IHC staining in Luminal A, Luminal B, HER2(+) and TNBC subtypes of breast cancer tissues. Magnification, ×200; scale bars, 100 μm. (D) Scatter dot plots of PTK7 expression in tumors with different molecular subtypes. Data were analyzed using one-way ANOVA and Tukey’s multiple comparisons test and are shown as mean ± s.d. * P < 0.05, ** P < 0.01, **** P < 0.0001. ns, no significance.

Journal: Frontiers in Oncology

Article Title: Protein Tyrosine Kinase 7 Regulates EGFR/Akt Signaling Pathway and Correlates With Malignant Progression in Triple-Negative Breast Cancer

doi: 10.3389/fonc.2021.699889

Figure Lengend Snippet: PTK7 expression is upregulated in breast cancer. (A) Box plots of PTK7 expression in breast invasive carcinoma (BRCA) using GEPIA: Gene Expression Profiling Interactive Analysis system ( http://gepia.cancer-pku.cn/ ). BRCA tumor (T) and non-tumor (N) TCGA normal and GTEx dataset included 1,085 tumor cases (T) and 291 non-tumor cases (N) was selected to observe the expression of PTK7. (B) IHC staining of PTK7 expression in breast cancer tissue microarray. (C) Representative images from PTK7 IHC staining in Luminal A, Luminal B, HER2(+) and TNBC subtypes of breast cancer tissues. Magnification, ×200; scale bars, 100 μm. (D) Scatter dot plots of PTK7 expression in tumors with different molecular subtypes. Data were analyzed using one-way ANOVA and Tukey’s multiple comparisons test and are shown as mean ± s.d. * P < 0.05, ** P < 0.01, **** P < 0.0001. ns, no significance.

Article Snippet: For PTK7 genetic alteration analysis in invasive breast carcinoma, cBioPortal for Cancer Genomics ( http://www.cbioportal.org/ ) breast cancer datasets were used which includes 1,904 patients with Agilent microarray data (METABRIC, Nature 2012 & Nat Commun 2016).

Techniques: Expressing, Immunohistochemistry, Microarray

Upregulation of PTK7 is related to metastasis and TNM stage in TNBC. (A) TNBC samples from 280 subjects of breast cancer tissue microarray were selected and divided into three groups based on TNM stages (AJCC staging). Representative images of IHC staining of PTK7 expression in the three groups (stage I, II and III) are shown. Magnification, ×200; scale bars, 100 μm. (B) Scatter dot plots of PTK7 scores in the three groups described in (A) . Data were analyzed using one-way ANOVA and are shown as mean ± s.d. * P < 0.05. (C) The percentage of cases in the groups described in (A) . Data were analyzed using Pearson’s χ 2 test. Light grey, low PTK7 level (IHC score 0~4); dark grey, medium PTK7 level (IHC score 5~8); black, high PTK7 level (IHC score 8~12). (D) TNBC samples were divided into two groups based on lymph node metastasis. Representative images of PTK7 staining in TNBC with or without lymph node metastasis are shown. Magnification, ×200; scale bars, 100 μm. (E) Scatter dot plots of PTK7 scores in the two groups described in (D) . Data were analyzed using one-way ANOVA and are shown as mean ± s.d. * P < 0.05. (F) The percentage of cases in the groups described in (D) . Data were analyzed using Pearson’s χ 2 test. Light grey, low PTK7 level (IHC score 0~4); dark grey, medium PTK7 level (IHC score 5~8); black, high PTK7 level (IHC score 8~12). ns, no significance.

Journal: Frontiers in Oncology

Article Title: Protein Tyrosine Kinase 7 Regulates EGFR/Akt Signaling Pathway and Correlates With Malignant Progression in Triple-Negative Breast Cancer

doi: 10.3389/fonc.2021.699889

Figure Lengend Snippet: Upregulation of PTK7 is related to metastasis and TNM stage in TNBC. (A) TNBC samples from 280 subjects of breast cancer tissue microarray were selected and divided into three groups based on TNM stages (AJCC staging). Representative images of IHC staining of PTK7 expression in the three groups (stage I, II and III) are shown. Magnification, ×200; scale bars, 100 μm. (B) Scatter dot plots of PTK7 scores in the three groups described in (A) . Data were analyzed using one-way ANOVA and are shown as mean ± s.d. * P < 0.05. (C) The percentage of cases in the groups described in (A) . Data were analyzed using Pearson’s χ 2 test. Light grey, low PTK7 level (IHC score 0~4); dark grey, medium PTK7 level (IHC score 5~8); black, high PTK7 level (IHC score 8~12). (D) TNBC samples were divided into two groups based on lymph node metastasis. Representative images of PTK7 staining in TNBC with or without lymph node metastasis are shown. Magnification, ×200; scale bars, 100 μm. (E) Scatter dot plots of PTK7 scores in the two groups described in (D) . Data were analyzed using one-way ANOVA and are shown as mean ± s.d. * P < 0.05. (F) The percentage of cases in the groups described in (D) . Data were analyzed using Pearson’s χ 2 test. Light grey, low PTK7 level (IHC score 0~4); dark grey, medium PTK7 level (IHC score 5~8); black, high PTK7 level (IHC score 8~12). ns, no significance.

Article Snippet: For PTK7 genetic alteration analysis in invasive breast carcinoma, cBioPortal for Cancer Genomics ( http://www.cbioportal.org/ ) breast cancer datasets were used which includes 1,904 patients with Agilent microarray data (METABRIC, Nature 2012 & Nat Commun 2016).

Techniques: Microarray, Immunohistochemistry, Expressing, Staining

PTK7 regulates EGFR-PI3K-Akt pathway in breast cancer. (A) PTK7 co-expression analysis in invasive breast carcinoma using breast cancer datasets including 1,904 patients with Agilent microarray data ( http://www.cbioportal.org/ ) and 374 PTK7 positively- (Spearman’s correlation > 0.3, P < 0.01) and 289 PTK7 negative- (Spearman’s correlation < -0.3, P < 0.01) correlated genes were selected and used as candidate genes in the following analysis. (B) PTK7 positively-correlated genes were analyzed using Kyoto Encyclopedia of Genes and Genomes (KEGG) by DAVID: Functional Annotation Tools ( https://david.ncifcrf.gov/tools.jsp ). PTK7 positively correlated genes enriched in PI3K-Akt signaling (hsa04151) and Regulation of actin cytoskeleton (hsa04810) pathways are listed in the frames, respectively. (C) PTK7 and EGFR pair-wise gene correlation in breast invasive carcinoma were analyzed using GEPIA Correlation Analysis tools ( http://gepia.cancer-pku.cn/detail.php?clicktag=correlation ). (D, E) MDA-MB-468 (D) and MDA-MB-231 (E) cells were transduced with a non-targeting control shRNA (shNC) or two different PTK7-specific shRNAs (shPTK71 and shPTK7#2). Cells were stimulated with EGF (500 ng/ml) for 0, 20 or 40 minutes and phospho-EGFR and phosphor-Akt levels were evaluated using immunoblotting assay.

Journal: Frontiers in Oncology

Article Title: Protein Tyrosine Kinase 7 Regulates EGFR/Akt Signaling Pathway and Correlates With Malignant Progression in Triple-Negative Breast Cancer

doi: 10.3389/fonc.2021.699889

Figure Lengend Snippet: PTK7 regulates EGFR-PI3K-Akt pathway in breast cancer. (A) PTK7 co-expression analysis in invasive breast carcinoma using breast cancer datasets including 1,904 patients with Agilent microarray data ( http://www.cbioportal.org/ ) and 374 PTK7 positively- (Spearman’s correlation > 0.3, P < 0.01) and 289 PTK7 negative- (Spearman’s correlation < -0.3, P < 0.01) correlated genes were selected and used as candidate genes in the following analysis. (B) PTK7 positively-correlated genes were analyzed using Kyoto Encyclopedia of Genes and Genomes (KEGG) by DAVID: Functional Annotation Tools ( https://david.ncifcrf.gov/tools.jsp ). PTK7 positively correlated genes enriched in PI3K-Akt signaling (hsa04151) and Regulation of actin cytoskeleton (hsa04810) pathways are listed in the frames, respectively. (C) PTK7 and EGFR pair-wise gene correlation in breast invasive carcinoma were analyzed using GEPIA Correlation Analysis tools ( http://gepia.cancer-pku.cn/detail.php?clicktag=correlation ). (D, E) MDA-MB-468 (D) and MDA-MB-231 (E) cells were transduced with a non-targeting control shRNA (shNC) or two different PTK7-specific shRNAs (shPTK71 and shPTK7#2). Cells were stimulated with EGF (500 ng/ml) for 0, 20 or 40 minutes and phospho-EGFR and phosphor-Akt levels were evaluated using immunoblotting assay.

Article Snippet: For PTK7 genetic alteration analysis in invasive breast carcinoma, cBioPortal for Cancer Genomics ( http://www.cbioportal.org/ ) breast cancer datasets were used which includes 1,904 patients with Agilent microarray data (METABRIC, Nature 2012 & Nat Commun 2016).

Techniques: Expressing, Microarray, Functional Assay, Transduction, shRNA, Western Blot